In March 2006, Lamborghini presented a new version of its halo car at the Geneva Motor Show; the Murciélago LP640. The new designation accompanying the car's name indicated the engine's position and orientation within the car (Longitudinale Posteriore, or "Rear Longitudinal"), and referenced the V12 engine's uprated power output; with its displacement increased to 6.5 litres, the engine in the new car made 640 PS (471 kW; 631 hp) at 8000 rpm.
The Murciélago's exterior received a minor facelift, with revised front and rear fascias and side air intakes. A new exhaust system is shaped into the rear diffuser, and the left-hand side air intake is enlarged to accommodate the oil cooler. A revised suspension , a launch control system, and an all-wheel drive system round out the performance modifications. A new 6-speed "E-gear" sequential automatic transmission became available as well. The LP640 wears 335/30 tires on its rear wheels.